Mpox Outbreak in South Africa – Africa CDC

Addis Ababa, 13 June – On 13 Might 2024, the Authorities of South Africa introduced an outbreak of Mpox following the affirmation of a case from Gauteng province with no journey historical past to international locations with an lively Mpox outbreak. As of at the moment, a complete of seven laboratory-confirmed instances and two deaths (Case Fatality Ratio – CFR: 28.6%**, *based mostly on hospitalized instances) had been reported from Gauteng (3/7), KwaZulu-Natal (3/7), and Western Cape (1/7) provinces. The instances had been confirmed on the Nationwide Institute for Communicable Illnesses (NICD) of South Africa.

All of the instances had been categorized as extreme instances of Mpox and required hospitalization. All instances are male, between the ages of 30 and 39 with co-morbidities (HIV-positive), and 5 of the seven recognized as “males who’ve intercourse with males.”

Preliminary investigations point out that each one the confirmed instances had no historical past of journey to international locations with ongoing Mpox outbreaks.

Accessible sequence information from three instances revealed the circulation of Clade IIb in South Africa. Clade IIb led to the biggest multi-country Mpox outbreak in 2022.

The Ministry of Well being has deployed fast response groups to assist additional investigations. Contacts of the confirmed instances are being monitored for 21 days. Moreover, lively case search, case administration, and threat communication are ongoing in affected communities.

On June 13, 2024, H.E. Dr. Jean Kaseya, Director Normal of Africa CDC, met with Hon. Joe Phaahla, Minister of Well being, and Dr. Sandile Buthelezi, Director Normal of the Nationwide Division of Well being, to evaluate the state of affairs and coordinate the response to this outbreak.

“At Africa CDC, we commend the management and efforts of the South African authorities in managing this outbreak and respect the assist from companions like WHO. We’re dedicated to supporting South Africa in securing the mandatory doses of Mpox vaccines, and constructing capability for event-based surveillance specializing in neighborhood and well being facility. An Mpox outbreak anyplace is a menace all over the place. We name for swift and pressing motion to extend entry to Mpox diagnostics, vaccines and therapeutics for all affected African international locations.”stated Dr. Jean Kaseya, the Director Normal of the Africa CDC.

Since January 2024, seven African international locations have reported Mpox, with a complete of 8,479 instances and 401 deaths as of June 14, 2024. Notably, 97% of those instances are from the Democratic Republic of Congo.

In response to this dire state of affairs, Africa CDC held a high-level emergency assembly on Mpox within the DRC in April 2024. The assembly underscored the crucial want for well timed, correct, and high-quality information on the Mpox to tell decision-making and program interventions. Ministers of Well being from Angola, Benin, Burundi, Cameroon, Central African Republic, Congo, Democratic Republic of Congo, Gabon, Ghana, Liberia, Nigeria, and Uganda, together with companions, emphasised the pressing must strengthen preparedness and response to Mpox in Africa. They highlighted the need for cross-border built-in illness surveillance and a coordinated provide of medical countermeasures like diagnostics, vaccines and therapeutics as a part of the Pathogen Entry and Profit Sharing (PABS).

Mpox is a zoonotic viral illness that primarily infects people and animals (e.g., rodents and primates). Mpox might be transmitted by means of direct contact (e.g., contact with lesions, physique fluids, or contaminated supplies) with contaminated animals or people or publicity to their respiratory droplets. The Case Fatality Ratio (CFR) of Mpox ranges between 0-11% within the normal inhabitants.


*The CFR was estimated solely among the many hospitalized Mpox instances. It doesn’t mirror the CFR of Mpox within the normal inhabitants.

About Africa CDC

About Africa CDC: The Africa Centres for Illness Management and Prevention (Africa CDC) is the African Union’s continental autonomous public well being company that helps member states in strengthening well being methods and enhancing surveillance, emergency response, and prevention and management of ailments. Study extra at:

Media Contact Margaret Edwin, Director of Communication & Public Data Division: Africa CDC Tel: +251 986 632 878 | E-mail:

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